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Research roadmap paves the way for UK synthetic biology


13 July 2012
  • Minister presented with roadmap to establish UK lead role in international synthetic biology
  • Shared vision provides first step towards realising the potential of synthetic biology
  • Expert report: synthetic biology could offer significant UK economic growth

Minister for Universities and Science, David Willetts, was presented with a Synthetic Biology Roadmap today which provides the vision and direction for supporting a world-leading synthetic biology community in the UK. The publication, produced by an independent panel of experts for the government’s Department for Business Innovation and Skills, sets out a shared vision for realising the potential of synthetic biology in the UK.

The roadmap aims to deliver a synthetic biology sector that is cutting edge; economically vibrant, diverse and sustainable; and of clear public benefit.

Welcoming the roadmap, Minister for Universities and Science, David Willetts, said: “Synthetic Biology has the ability to revolutionise major industries in bio-energy and bio-technology in the UK. If we develop this exciting area to its full potential there are fantastic opportunities in sectors such as bio-fuel and medical care that are largely untapped. This roadmap positions the UK as a leader in global synthetic biology, which presents significant growth and employment opportunities.”

The recommendations in the roadmap provide a compass-bearing for the synthetic biology community, helping to align interests towards future growth opportunities, whilst identifying the resources and support needed to accelerate progress in the shorter term.

The roadmap outlines five key recommendations:

  1. Invest in a network of multidisciplinary centres to establish an outstanding UK synthetic biology resource.
  2. Build a skilled, energised and well-funded UK-wide synthetic biology community.
  3. Invest to accelerate technology responsibly to market.
  4. Assume a leading international role.
  5. Establish a leadership council.

Lionel Clarke, Chairman of the UK Synthetic Biology Roadmap Coordination Group, said: “Synthetic biology has the potential to deliver significant benefits, addressing important challenges and generating exciting opportunities for growth – but much work needs to be done and has to be done responsibly. Engaging the synthetic biology community in shaping this roadmap has contributed a first step towards realising this potential, through building a shared vision.”

Synthetic biology is the design and engineering of biologically based parts, novel devices and systems as well as the redesign of existing, natural biological systems, for a useful purpose. It has the potential to deliver important new applications and improve existing industrial processes – resulting in economic growth and job creation.

Specific applications are already emerging, but its long-term potential for a range of industrial sectors (e.g. industrial biotechnology, bioenergy and healthcare) remains largely untapped. Applications could include biosensors to identify infections; more personalised medicines; improved waste treatments; and more cost-effective routes to renewable chemicals, materials and fuels. A recent assessment by BCC research on behalf of Global Information Inc concluded that the value of the global synthetic biology market will grow from $1.6bn in 2011 to $10.8bn by 2016.

A coordination group steered the development of a Synthetic Biology Roadmap and included a wide range of stakeholders, including academics, industrialists and, on behalf of the Research Councils, the Biotechnology and Biological Sciences Research Council (BBSRC), Engineering and Physical Sciences Research Council (EPSRC) and the Technology Strategy Board (TSB).

Professor Douglas Kell, Chief Executive of BBSRC, said: “The UK is world-leading on the global stage of bioscience and, thanks to huge progress in our understanding of biological systems, we have reached an important milestone in realising the capacity of synthetic biology to develop useful applications.”

“We have the perfect environment to be leaders in the internationally-expanding field of synthetic biology and this roadmap will help the community to deliver responsibly and in a coordinated way. BBSRC has made big investment in this area, recognising the important role that it can play in addressing many of the grand challenges we face, and in helping to provide future prosperity.”

Professor David Delpy, Chief Executive of EPSRC said: "Synthetic Biology is an area of strategic priority for the Engineering and Physical Sciences Research Council (EPSRC), we have already invested in research and wish to see it continue to grow. The engineering and physical sciences community has a crucial role to play in how synthetic biology develops."

Iain Gray, Chief Executive of the TSB, said: “The UK is developing world leading capability in synthetic biology, particularly in the research base, and the roadmap charts how UK businesses could use this emerging technology responsibly to deliver future growth and create jobs through developing new products, applications, processes and services.”

The recommendations in the roadmap point towards multidisciplinary synthetic biology centres in existing higher education establishments and an extension of the UK-wide synthetic biology community. The formation of an overarching network, an annual forum, and funding competitions to support the development of novel applications were also suggested.

Responsible research and innovation was a key theme in the document, including the need for awareness, training and adherence to regulatory frameworks. The roadmap sets out plans to ensure that this technology continues to be developed in a socially responsible fashion. The UK has already initiated public dialogue in synthetic biology and encouraged interaction between regulators and funders.

The need for the UK to build on its current strengths and assume a leading international role in synthetic biology to set standards and shape future regulations was also highlighted and recommendations included participating in trans-national grant funding, hosting international conferences and continuing to foster coordinated efforts in synthetic biology through research partnerships.

The roadmap was presented to the Minister during a visit to TMO Renewables, a UK company, established with long-term support from BBSRC, which uses synthetic biology techniques in the production of renewable fuels and chemicals.

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Further information

Contact:
Rob Dawson
BBSRC Head of News
Tel: 01793 413 204 or email: Rob Dawson

Notes to editors

  1. More information about the synthetic biology roadmap is available here.

  2. About the Synthetic Biology Roadmap

    The synthetic biology approach is to engineer biological systems to perform new functions in a modular, reliable and predictable way, allowing modules to be reused in different contexts. It has the potential to deliver important new applications and improve existing industrial processes across many sectors including healthcare, energy, pharmaceuticals, materials, and remediation – resulting in economic growth and job creation.

    The primary purpose of this technology roadmap is to establish a vision for synthetic biology in the UK, and to identify the processes that must be applied to realise it. It provides a framework within which to consider future options and coordinate actions. Because synthetic biology is an emerging and fast-developing sector, the purpose of the roadmap is not to provide a detailed project plan but, more importantly, to determine those core elements that need to be put in place as a secure platform upon which innovative developments may build in future.

    This roadmap has been produced during 2012 by an independent panel of experts at the request of the UK Department for Business Innovation and Skills. It incorporates material generated during two UK roadmap workshops attended by 70 participants representing a broad range of stakeholders from industry, public bodies, academia and other organisations. The workshops followed a process established through extensive experience by the Institute for Manufacturing (IfM) in Cambridge, ensuring substantial engagement of all participants and generating a wealth of valuable material and insights. The roadmap has also been heavily informed by the large and rapidly growing body of world literature and the outputs of the numerous conferences, symposia and discussion forums that have focused on synthetic biology in recent years.

  3. Biotechnology and Biological Sciences Research Council

    BBSRC invests in world-class bioscience research and training on behalf of the UK public. Our aim is to further scientific knowledge, to promote economic growth, wealth and job creation and to improve quality of life in the UK and beyond.

    Funded by the UK Government, and with an annual budget of around £445M (2011-2012), we support research and training in universities and strategically funded institutes. BBSRC research and the people we fund are helping society to meet major challenges, including food security, green energy and healthier, longer lives. Our investments underpin important UK economic sectors, such as farming, food, industrial biotechnology and pharmaceuticals.

    More information about BBSRC, our science and our impact.

    More information about BBSRC strategically funded institutes.

  4. Engineering and Physical Sciences Research Council (EPSRC)

    The Engineering and Physical Sciences Research Council (EPSRC) is the UK’s main agency for funding research in engineering and the physical sciences. EPSRC invests around £800 million a year in research and postgraduate training, to help the nation handle the next generation of technological change. The areas covered range from information technology to structural engineering, and mathematics to materials science. This research forms the basis for future economic development in the UK and improvements for everyone’s health, lifestyle and culture. EPSRC works alongside other Research Councils with responsibility for other areas of research. The Research Councils work collectively on issues of common concern via Research Councils UK.

  5. The Technology Strategy Board

    The Technology Strategy Board is the UK’s innovation agency. Its goal is to accelerate economic growth by stimulating and supporting business-led innovation. Sponsored by the Department for Business, Innovation and Skills (BIS), the Technology Strategy Board brings together business, research and the public sector, supporting and accelerating the development of innovative products and services to meet market needs, tackle major societal challenges and help build the future economy.