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MOD’s Policy for Biological Monitoring for DU on operations: a public paper

January 2003

Gulf Veterans’ Illnesses Unit, Ministry of Defence, St George's Court,
2-12 Bloomsbury Way, London WC1A 2SH
Tel 020 73054643

Background

As part of the consultation process for MOD’s proposed screening programme for Depleted Uranium (DU), which took place in the first half of 2001, MOD sought views on its proposals for Biological Monitoring on current and future military operations. The two public consultation papers on DU screening and two corresponding papers summarising the responses are published on the MOD web site (www.mod.uk).

A range of views was expressed on the detail of MOD’s proposals for biological monitoring, but it was agreed that biological monitoring should be introduced and that testing for DU as well as total uranium might be necessary in certain circumstances. Some respondents doubted the practicalities of monitoring during some military operations.

Other responses recommended that independent experts should be consulted on the technical aspects of the monitoring, and Ministers established an independent Depleted Uranium Oversight Board (DUOB) (www.duob.org.uk) which was invited to comment on the technical aspects of the development of biological monitoring tests to be used by MOD for future operations where DU is used."

Policy and Purpose of Biological Monitoring

Having taken into account the responses to the public consultation exercises and comments from the DUOB, the MOD has now developed, within its overall health and safety framework, its policy for biological monitoring on current and future operations.

The policy is that Biological Monitoring for DU will be implemented with immediate effect for military personnel and MOD civilians on operations where they have been exposed to DU or where there is a high probability that they have been so exposed.

Health and safety is an employer’s responsibility and therefore the policy only applies to military personnel and MOD civilians. However, details of the policy will be made available at no cost to other UK organisations and personnel, such as MOD contractors and members of Non Governmental Organisations, who may be, or who may have been, legitimately present in operational theatres where DU munitions may have been used. Anyone not employed by the Secretary of State for Defence may access the facilities and services described in this document on a repayment basis.

The purpose of Biological Monitoring is to provide information to assist in risk communication and dose assessment. It will also provide information to assist in medical treatment in the very unlikely event that any toxic effects from DU may develop.

The details which follow on the implementation of the biological monitoring programme may evolve over time to take account of experience gained and future scientific developments.

Exposure Categories

In order to assist with prioritisation for monitoring of potentially exposed personnel, the MOD biological monitoring policy has been based on the allocation of personnel to one of 3 exposure categories. These categories are designated as Levels I - III and were initially developed for use in some DU munitions risk assessments such as those described in the Royal Society Part I report (The Health Hazards of Depleted Uranium Munitions, May 2001). However, in recognition of some veterans’ concerns, MOD has extended the definition of Level III personnel to include everyone in a military theatre of operations. The MOD categories are:

a. Level I. Personnel in a platform (ie a vehicle or similar) struck by a DU penetrator, or personnel entering the platform immediately afterwards, typically to assist injured colleagues. Any exposure will be dominated by inhalation of the aerosol generated by the impact and the platform crew will also be at risk from embedded DU shrapnel fragments.

b. Level II. Personnel working in or on contaminated vehicles to carry out repairs etc. Any exposure will be dominated by inhalation from the re-suspension of DU deposited within the contaminated vehicle. Exposures will be kept as low as reasonably practicable as information is available on the nature of the potential risks from DU and on the means by which troops may restrict any possible exposures, for example through the use of equipment and procedures.

c. Level III. All other personnel in theatre, particularly those downwind of platform fires, those entering damaged platforms briefly and those transiting through potentially contaminated areas. Information on the potential risks from DU and on methods of restricting exposure is available as for Level II personnel.

Identification of an individual’s exposure level

Level Is and IIs will be notified to the medical staff by unit commanders, "on-the-scene" medical staff and, on occasion by the individual his/herself. Level IIs will normally fall within certain occupational groups such as REME or EOD personnel; such groups entering known contaminated areas in controlled circumstances will be appropriately protected.

Collection of Samples

Arrangements are to be made to collect urine samples from all Level I and Level II personnel, and from those Level III personnel who so choose (see below), following the instructions in Annex A. The sample analysis for Levels I and II is to identify the concentrations of uranium isotopes in the urine.

Level III personnel are to receive information that will allow them to make an informed choice as to whether they wish to participate in a monitoring programme that will consist of a determination of the total uranium content in the urine. The concentrations of uranium isotopes in the urine will also be determined if anomalous results (as defined below) are obtained.

A briefing on the availability of biological monitoring will be included in standard pre-deployment briefings when risk assessments indicate that DU exposures may occur. In addition a generic offer of screening to all who served in a theatre where DU munitions were used will be part of the theatre exit process.

Sample collection will be carried out at the home base or in role 4 hospital care, unless medical advice is to collect the sample in theatre. Collection will take place as soon as practicable but within a year of exposure. Priority will be given to those within Levels I and II. Information on the circumstances of the potential exposure will be obtained when samples are collected.

Sample Handling and Assessment of Results

Samples will be returned to the Approved Dosimetry Service (ADS) at the Institute of Naval Medicine who will record receipt of each sample and arrange for its analysis. The analysis will include an assessment of the dose received and an interpretation of the results. The ADS will also enter the analysis results onto MOD's Approved Radiation Dose Record Keeping System and send a copy of the results to the originating unit/body.

To assist the interpretation, the results of the monitoring will be assessed against the results of background uranium in urine levels determined through the work currently being overseen by the DUOB.

Re-testing and/or additional tests will be carried out where indicated in accordance with statutory requirements. A variety of techniques (such as whole body monitoring) may be used, as recommended by radiation medicine specialists and the MOD’s Radiation Protection Adviser.

Reporting of results to individuals

Results will be transmitted to service personnel via the forces’ medical staff using existing procedures. In the case of civilians, results will be transmitted via their employer, occupational health provider or GP.


Annex A: COLLECTION & ANALYSIS OF URINE SAMPLES FOR ESTIMATION OF DEPLETED URANIUM (DU) EXPOSURE.

A.1 Requirement. Urine samples will be collected from individuals in accordance with the preceding policy on biological monitoring for DU exposure.

A.2 Sample containers. Containers will be supplied by the chosen analytical laboratories, probably via the Approved Dosimetry Service (ADS), on request. The issued sample sets will include UN/IATA approved outer packaging to allow transport by all routes including air. This packaging will typically consist of a sealable secondary container to hold the urine samples and an outer cardboard casing. Containers held by sickbays and medical centres are not suitable and are not to be used for these samples.

A.3 Sample collection. In order to avoid contamination of samples, samples should normally be collected in a clean area within a medical facility under appropriate supervision at home base or in role 4 hospital care as soon as practicable but within a year of exposure. However, samples may also be collected in theatre under less than ideal conditions when there is an urgent medical need; instructions for this are provided below. Detailed collection instructions will vary with the laboratory concerned but a typical procedure is to request persons to provide a single 50ml midstream urine sample. The inner container may then be labelled with name, service number, date of collection and any other information requested by the laboratory. If preservative is included, the container with the sample should be vigorously shaken to disperse the preservative. It may then be necessary to store the container refrigerated.

A.4 Transport of samples. Return instructions will be supplied with the sample containers. After collection and labelling the samples should be packed into the supplied packaging and transported to the nominated laboratory by the fastest route.

A.5 Method of analysis. The analysis method will depend on the laboratory (ies) concerned. Samples from level I and II exposures will be analysed directly for both isotope ratio and uranium concentration. The method used is likely to be that currently under development by the DUOB. For level III exposures the initial analysis will be a screening test for total uranium. A probable methodology for this test will be flow injection Inductively Coupled Plasma Mass Spectrometry (ICP/MS) using a quadropole mass spectrometer. This test has a sufficiently low limit of detection to ensure that any increase in uranium excretion is detected. Further sample analysis to establish isotope ratio will be an option for those individuals considered to have significant exposure.

A.6 Sampling in theatre. Uranium is a naturally occurring element and can be found, at low levels, in dust and other environmental materials. If dust is introduced into the sample the resultant uranium concentration will be incorrect. In exceptional cases where it is deemed necessary to undertake sampling in theatre, the following precautions are to be observed:

a. Where practicable provide the patient with freshly laundered clothing before collecting the sample.

b. Where practicable collect samples in a clean area within a medical facility under appropriate supervision.

c. Patients must wash their hands prior to providing a sample.

d. Medical personnel must also wash their hands prior to handling samples.


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Last Updated: 22 May 03