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On 4 July 2007, the Prime Minister and Health Secretary announced that Lord Darzi would lead a review of the NHS that would advise on how to meet the challenges of delivering health care over the next decade.

Lord Darzi also holds the Paul Hamlyn Chair of Surgery at Imperial College London and is an honorary consultant at St Mary's Hospital and The Royal Marsden.

Lord Darzi and his team are respected internationally for their innovative work in the advancement of minimal invasive surgery, and in the development and use of allied technologies including surgical robots and image guided surgery. Lord Darzi actively pursues, and relentlessly campaigns for, the need for improved inter-disciplinary research.  
 
The innovative work of Lord Darzi and his team is globally recognised. They have been awarded many prizes including the Queen’s Anniversary Prize for Excellence in Higher and Further Education in 2001. The prize was given in recognition for pioneering new technologies to address training requirements for trainee surgeons, surgeons in post and other professionals.
 
Lord Darzi was knighted by the Queen as a Knight Commander of the most excellent Order of the British Empire (KBE) in December 2002 for his service to medicine and surgery.