Government departments with significant R&D spend each have their own Departmental Chief Scientific Adviser (DCSA) and DCSAs work together on cross-cutting issues
In some cases the GCSA leads in advising the Government on major cross-cutting issues, working with other DCSAs. In doing so he engages the best scientists nationally and often internationally to help him and ensure that his advice is as robust as possible.
More information regarding the roles and responsibilities of DCSAs can be found in the Guidance to Government Departments on using science.