The 80th was the last of the four Regiments to see action under its old number. It took part in the Zulu War, forming the front of the British square at the decisive Battle of Ulundi, and was also engaged in minor operations against a Kaffir chief named Sekukuni. Two VCs were won:
By Private S Wassall on 22 January 1879 when, under heavy fire, he saved the life of a comrade struggling in the Buffalo River.
By CSgt A Booth who, on 12 March 1879, fought his way to safety with the survivors from a detachment surprised by a Zulu night attack.